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What makes methamphetamine such an attractive high? Meth users report that after taking the drug they experience a sudden 'rush' of pleasure or a prolonged sense of euphoria, as well as increased energy, focus, confidence, sexual prowess and feelings of desirability. However, after that first try, users require more and more of the drug to get that feeling again, and maintain it. With repeated use, methamphetamine exacts a toll on the mind and body, robbing users of their physical health and cognitive abilities, their libido and good looks, and their ability to experience pleasure. Here's how the body reacts to meth and the consequences of long-term abuse.

Although this is an obvious long-term consequence of crack use, its wide-ranging consequences should not be ignored. Addiction ultimately occurs because the brain cannot function effectively with the excessive levels of neurotransmitters created by crack consumption. Loss of lateral eyebrows, or madarosis, has also been noted in users as a result of hot fumes contacting the face [3,49]. “Crack hands” or black, hyperkeratotic,.

Meth and the Brain • Meth releases a surge of dopamine, causing an intense rush of pleasure or prolonged sense of euphoria. • Over time, meth destroys dopamine receptors, making it impossible to feel pleasure. • Although these pleasure centers can heal over time, research suggests that damage to users' cognitive abilities may be permanent. • Chronic abuse can lead to psychotic behavior, including paranoia, insomnia, anxiety, extreme aggression, delusions and hallucinations, and even death. 'There [are] a whole variety of reasons to try methamphetamine,' explains Dr. Richard Rawson, associate director of UCLA's Integrated Substance Abuse Programs. '[H]owever, once they take the drug their reasons are pretty much the same: They like how it affects their brain[s].'

7812 is a famous IC which is being widely used in 12V voltage regulator circuits. Truly speaking it is a complete standalone voltage regulator. We only need to use two capacitors, one on the input and second one on the output of 7812 in order to achieve clean voltage output and even these capacitors are optional to use. The ic 7812 is a positive voltage regulator which means that it generates the positive voltage with respect to the common ground. In case if both the positive and negative voltage supply is needed in the same circuit. Untuk IC ini, xx diganti dengan dua digit, yang menunjukkan output tegangan (misalnya, 7805 memiliki output 5 volt, sedangkan 7812 memproduksi 12 volt). 78xx adalah kode regulator yang bekerja pada tegangan positif: artinya mereka menghasilkan tegangan out put positif. Nah fungsi ic 7812 disini selain menstabilkan tegangan agar tetap stabil 12v, tidak naik dan turun. Anda juga bisa menggunakan kiprok sebagai pengganti diode. Pengganti ic 7812.

Meth users have described this feeling as a sudden rush of pleasure lasting for several minutes, followed by a euphoric high that lasts between six and 12 hours, and it is the result of drug causing the brain to release excessive amounts of the chemical dopamine, a neurotransmitter that controls pleasure. All drugs of abuse cause the release of dopamine, even alcohol and nicotine, explains Rawson, '[But] methamphetamine produces the mother of all dopamine releases.' For example, in lab experiments done on animals, sex causes dopamine levels to jump from 100 to 200 units, and cocaine causes them to spike to 350 units. '[With] methamphetamine you get a release from the base level to about 1,250 units, something that's about 12 times as much of a release of dopamine as you get from food and sex and other pleasurable activities,' Rawson says. 'This really doesn't occur from any normally rewarding activity. That's one of the reasons why people, when they take methamphetamine, report having this euphoric [feeling] that's unlike anything they've ever experienced.' Then, when the drug wears off, users experience profound depression and feel the need to keep taking the drug to avoid the crash.